INTRODUCTION
Type III diabetes also known as hybrid or double diabetes is a new and dangerous phenomenon. It is found that type III Diabetes affects brain insulin levels, and appears to be one of the major causes of Alzheimer's disease . Insulin receptors in the brain are sensitive to particles known as ADDL's.
Calotropis procera R. Br. (Asclepidaceae) is a shrub which widely distribute in the world. The plant is used in the treatment of many disease and disorder both in humans and veterinary application. The present work was undertaken to investigate the anti-diarrhoeal activity of ethanolic extract of root (200 mg/kg BW) of Calotropis procera against castor oil induced diarrhoea in experimental animal and was found to be significant results.
The whole 6 pages article is available for download here.
Bacteria are like living paint, covering nearly every surface imaginable and living within a variety of living and nonliving things. An antibiotic is any substance produced by a microorganism, which harms or kills another microorganism. However, antibiotics do not harm viruses. A majority of antibiotic substances are natural products that certain bacteria and fungi produce as a natural defense to send outside their cells.
The whole 9 pages article is available for download here.
The present investigation concerns the development of mucoadhesive tablets of Tramadol Hydrochloride which were designed to prolong the gastric residence time after oral administration. Tablets of Tramadol Hydrochloride were formulated using four mucoadhesive polymers namely guar gum, xanthan gum, HPMC K15M and HPMC K100M and carried out studies for its evaluation parameters. Formulations F15 and F16 containing polymers of Xanthan gum, HPMC K100M and HPMC K15M were established to be the optimum formulation since it shows optimum bioadhesive force, swelling index & desired evaluation standards. Further investigations are needed to confirm the in vivo efficiency, long term stability studies are needed to stabilize the controlled released formulations.
The whole 8 pages article is available for download here.
Microsphere technology has been studied extensively for the sustained delivery of therapeutic agents. Microspheres can be manufactured from various natural and synthetic materials. Glass microspheres, polymer microspheres and ceramic microspheres are commercially available. Recent researches are confined to the discovery of active microspheres in the treatment of cancers. The present paper review the recent approaches in microspheres technology, a novel drug delivers system.
The whole 6 pages article is available for download here.
Oil is an important source of fat and is important in human diet. The microbial limit tests are designed to perform the qualitative and quantitative estimations of specific viable microorganisms present in pharmaceutical substances or in the samples. The present paper deals with the various procedures in estimation of microbial limits in oils.
The whole 4 pages article is available for download here.
