A Novel Means of Greatly Extending Lifespan and Resistance to Oxidative Stress
Ten fold increase in lifespan is observed for the deletion of a single gene
The findings in C. elegans are that the deletion of a specific domain of the phosphoinositol-3-kinase (PI3K) gene results in a 10-fold increase in life span.
This pathway, and this gene, is known to limit lifespan on C. elegans and, with lesser evidence, thought to affect life span in...