Micro- and nanoscale technologies for tissue engineering and drug discovery applications

Micro- and nanoscale technologies are emerging as powerful enabling tools for tissue engineering and drug discovery. In tissue engineering, micro- and nanotechnologies can be used to fabricate biomimetic scaffolds with increased complexity and vascularization.

The whole 16 pages article is available for download here.   

Natural products as a gold mine for arthritis treatment

Arthritis, an inflammation of the joints, is usually a chronic disease that results from dysregulation of pro-inflammatory cytokines (e.g. tumour necrosis factor and interleukin-1b) and pro-inflammatory enzymes that mediate the production of prostaglandins (e.g. cyclooxygenase-2) and leukotrienes
(e.g. lipooxygenase), together with the expression of adhesion molecules and matrix metalloproteinases, and hyperproliferation of synovial fibroblasts. All of these factors are regulated by the activation of the transcription factor nuclear factor-kB. Thus, agents that suppress the expression of tumour necrosis factor-a, interleukin-1b, cyclooxygenase-2, lipooxygenase, matrix metalloproteinases or adhesion molecules, or suppress the activation of NF-kB, all have potential for the treatment of arthritis.

The whole 8 pages article is available for download here

A comprehensive review on nanoparticle drug delivery system

Nanoparticles (NP) are defined as particles with a diameter smaller than 100 nm, are increasingly used in different applications, including drug carrier systems and to pass organ barriers such as the blood-brain barrier. Because of their unique properties Nanocrystals (quantum dots) and other nanoparticles (gold colloids, nanobars, dendrimers and nanoshells) have been receiving a lot of attention for potential use in Therapeutics, Bioengineering and therapeutics drug discovery.

The whole 17 pages article is available for download here.

GSK and Online Communities Create Unique Alliance to Stimulate Open Source Drug Discovery for Malaria

  • GSK becomes first company to freely share chemical structures on 13,500 molecules from its compound library
  • Alliances formed with leading scientific research communities from private industry and public-domain data provider
Logos
May 19, 2010/Burlingame, CA/ GlaxoSmithKline (GSK) had teamed up with leading public-domain data providers European Bioinformatics Institute (EMBL-EBI), the U.S. National Library of Medicine (NLM) and the US-based informatics service provider Collaborative Drug Discovery (CDD) to make freely available key scientific information on more than 13,500 compounds that could ultimately lead to new treatments for malaria. 
Global medicine

Beyond Brexit and EU Falsified Medicine Directive

SMi Group Reports: (2016.11.16, London, UK): Over 90 senior leaders in parallel trade will meet in London in February 2017 to discuss upcoming trends and share best practices.


With Brexit and the new EU Falsified Medicine Directive, what does the future hold for parallel trade? SMi’s Parallel Trade conference will be returning to London next February 6th-7th, for its 11th year, to discuss short term and long term concerns of pharma manufacturers, regulators and parallel traders. They will engage in an interactive debate and discuss how to keep abreast of the current trends and how to overcome all challenges.

Health authorities, associations and academic sectors in the GCC to collaborate in the advancement of pharmacy practice in the region

Dubai, 16 August 2015:

The shift from product to patient-centered practice in pharmacy is said to be a leading trend in the globe nowadays. The GCC region, believed by some experts to witness rapid developments in its pharmacy practice and education, is among those who are moving towards this trend.

Dr. Lamia Yahya, Clinical Pharmacist at Corniche Hospital in the UAE, believes that the pharmacy practice in the region is booming and is an actively growing profession. "It had moved away from the classic role of just ‘handing in' the medication to the patient, to more orientation towards patient care," she adds. However, some expert suggests that the entire region should place a great emphasis to effectively further advance the profession. An expert from Qatar, Dr. Ahmed Nadir Kheir, Associate Professor and Continuing Professional Pharmacy Development (CPPD) Coordinator for Qatar University, shares that one of the most important factors and tools of change is the advancement in pharmacy education and the emergence of accreditation initiatives, which target quality in health care.

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