Recent Aspects of Pulmonary Drug Delivery System - An Overview

Pulmonary delivery of drugs has become an attractive target in the health care industry as the lung is capable of absorbing pharmaceuticals either for local deposition or for systemic delivery. Half of all pharmaceuticals are not soluble in water, but are soluble in lipid. As the lung is able to absorb both water and oil into the tissue, this is not a limitation of pulmonary delivery. However, existing jet nebulizers cannot aerosolize viscous liquids and ultrasound nebulizers destroy drug emulsions, thereby greatly limiting the potential use of pulmonary drug delivery.

The whole 17 pages article is available for download here.

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Nanotechnology in Medicine – An Overview

Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced. Nanotechnology enhanced materials will enable a weight reduction accompanied by an increase in stability and an improved functionality. Biomedical nanotechnology, bionanotechnology, and nanomedicine are used to describe this hybrid field. The prefix "nano" refers to one-billionth. When applied in the metric scale of linear measurements, a nanometer is one-billionth of a meter. The term "nanotechnology" is now commonly used to refer to the creation of new objects with nanoscale dimensions between 1.0 and 100.0 nm.

The whole 15 pages article is available for download here.

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Gastroretentive Drug Delivery System - An Overview

In recent years scientific and technological advancements have been made in the research and development of controlled release oral drug delivery systems by overcoming physiological adversities like short gastric residence times and unpredictable gastric emptying times. Gastroretentive drug delivery systems are the systems which are retained in the stomach for a longer period of time and thereby improve the bioavailability of drugs.

The whole 16 pages article is available for download here.

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Recent Trends of Zinc in Health and Chronic Disease

Zinc is widely recognized as an essential micronutrient with a catalytic role in over a 100 specific metabolic enzymes in human metabolism. Zinc deficiency was a major etiological factor in the syndrome of adolescent nutritional dwarfism, that had been identified mid-eastern countries. Zinc is one of the most ubiquitous of all trace elements involved in human metabolism and plays multiple roles in the perpetuation of genetic materials, including transcription of DNA, translation of RNA and ultimately cellular division. It is thus critical to understand the role of zinc in health and disease, especially during the vulnerable periods of growth and development. In severe zinc deficiency the symptoms are slowing growth and development, delayed sexual maturation, chronic and severe diarrhea, impaired wound healing, diminished appetite, impaired taste sensation.

The whole 5 pages article is available for download here.

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Resent Aspect of Mouth Dissolving Tablet - An Overview

Recently pharmaceutical preparations used for elderly patients have been investigated to improve the treatment compliances and quality of life of patients. Recent advances in Novel Drug Delivery System (NDDS) aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is "Mouth Dissolving Tablet" The concept of Mouth Dissolving Drug Delivery System emerged from the desire to provide patient with conventional mean of taking their medication. Difficulty in swallowing (Dysphagia) is a common problem of all age groups, especially elderly and pediatrics, because of physiological changes associated with these groups of patients.

The whole 19 pages article is available for download here.

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A Review on Hyperlipidemic

Atherosclerosis is the major case of morbidity and mortality in the world today, accounting for half of death in world. The origin of atherosclerosis is attributed to diets rich in fats, tobacco, alcohol consumption and lack of physical activity along with genetic factors like increased insulin resistance, decreased beta cell function, diabetes mellitus, obesity, and elevated levels of LDL, triglycerides, with reduced HDL Cholesterol.

The whole 18 pages article is available for download here.

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