Prediction of Human Intestinal Permeability Single-Pass Intestinal Perfusion in Rat: A QSAR/QSPR Approach

The aim of the study was the prediction of human intestinal permeability and fraction absorbed of oral dose using QSAR/QSPR methods. To explore physicochemical and topological properties of 15 compounds responsible for their Human intestinal permeability, a quantitative structure activity relationship, Hansch approach was applied on sixteen compounds. Various physicochemical and topological descriptors and reported Human intestinal permeability values of different 15 compounds were used as independent variables and dependent variable respectively.

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Evaluation and Phytochemical Screening of Seed Oil of Nigella Sativa Linn.

Nigella sativa (Ranunculaceae) is a flowering plant, native to Southwest Asia. Seeds contain 36%–38% fixed oils, proteins, alkaloids, saponin and 0.4%–2.5% essential oil. The fixed oil is composed mainly of unsaturated fatty acids, including the unusual C20:2 arachidic and eicosadienoic acids. The seeds are used as a carminative and stimulant to ease bowel and indigestion problems and are given to treat intestinal worms and nerve defects to reduce flatulence, and induce sweating. The present paper deals with preliminary phytochemical screening of fixed oil obtained by the seeds. Also attempt was made to evaluate the oil so as to establish the standardization parameters.

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Folklore Uses of an Endangered Ethnomedicinal Herb of India Sarcostemma Acidum. (Somlata)

Herbal medicines are in great demand in both developed and the developing countries in primary healthcare because of their great efficacy and little or no side effects. These traditional systems of medicine together with homoeopathy and folklore medicine continue to play a significant role largely in the health care system of the population. The tribals and rural population of India are highly dependent on medicinal plant therapy for meeting their health care needs. This attracted the attention of several botanist and plant scientists of several medicinal plants and there was a spurt of scientific literature. Somlata (Sarcostemma acidum) belonging to the family Asclepiadacea grown in India, Europe and US is an underutilized crop. 

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Quantum Dots as multifunctional nanoparticles - A review

Quantum Dots (QDs) are one of the nanoparticles that use in imaging, recognition and targeting. QDs are nanometer-size luminescent semiconductor crystals and have unique chemical and physical properties due to their size and their highly compact structure. They emit different wavelengths over a broad range of the light spectrum from visible to infrared, depending on their size and chemical composition.

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Evaluation of the Technology for Biodiesel Production from Jatropha Curcas Oil and Acid Oil

In recent times, the world has been confronted with an energy crisis due to depletion of resources and increased environmental problems. The situation has led for search for an alternative fuel, which should be not only sustainable but also environmental friendly. Due to increase in the petroleum and the environmental concerns about pollution coming from the car gases, Biodiesel is becoming a developing area of high concern. For developing countries, fuels of bio-origin such as alcohol, vegetable oils, biomass, biogas, synthetic fuels etc. are becoming important.  

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Formulation and Comparative Evaluation of Dasamoolarist, an Ayurvedic Formulation

Kushwaha Ashok^1* and Aind Jaya Gladish²

1, Shri RNS College of Pharmacy, Gwalior, MP-India

2, Nimar Institute of Pharmacy, Dhamnod, Dhar, MP - India

Abstract

The present investigation was done to formulate and evaluated dasamoolaristam and compare the efficacy with the brand available in the market as per WHO and Indian Pharmacopoeial specifications. Various physicochemical parameters such as alcohol-soluble extractive, water-soluble extractive, total ash, acid-insoluble ash, total solid, and alcohol content were determined and compared.

Keywords: Dasamoolarist, Ayurvedic formulation, Evaluation

*Corresponding Author